Arizona will now be able to reject federal laws the state deems unconstitutional.
Proposition 122 narrowly passed with 51.25 percent of votes, while 48.75 percent of voters said "no."
This approves amending the state Constitution to allow the Legislature and the governor to reject funding of or enforcement for any federal law they deem unconstitutional.
Backers have called it a state sovereignty issue, saying Arizona should not be forced to pay for bad laws passed by Congress. They pointed to the Affordable Care Act as the top reason the amendment is on the ballot.
Opponents of Prop 122 said the change would itself be unconstitutional because it is not up to the Legislature to determine what is and is not unconstitutional.
On Election Day, voters also approved Prop 303, or "the right to try act," which will allow terminally ill patients use experimental drugs not yet fully tested.
Prop 304, a pay raise to state legislators, was rejected.
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